In general after five years of pursuing surveillance most patients are still in the program without progression. You’ll see that various studies have various drop out rates, usually with no medical consequence.
You’ll also notice that some drop out for anxiety issues.
The other most common reason for drop out would be a more unfavorable biopsy result or change in PSA value or velocity.
So, in the properly selected and appropriately followed patient , surveillance works. The unknown question however again is …who will be that guy that will fall through the cracks…that guy that is that “low percentage guy.” I was the anxiety guy..couldn’t live with it…I had to have it out and the biggest part of my decision was based on my age. What will it be for you…” How big a boy are you?”