If an elevated PSA goes down after antibiotics does that mean you don’t have prostate cancer?

Well…I see patients all the time who have had an elevated PSA in the past and their family M.D. put them on 2 weeks of Cipro and then had the PSA repeated. Often times the PSA will go to normal and the family M.D. will then repeat a PSA at say 6 months. Often times it is elevated again and then the patient is sent to the urologist. This scenario happened this morning in my office. The patient wanted to do antibiotics again and then repeat the PSA again before consenting to a biopsy. A reasonable approach. We redrew the PSA. His father, a doctor, told him not to consent to a biopsy and this was the patient’s mindset before I saw him as a patient. What we will do in terms recommendations will be heavily influenced by this patient’s preconceived ideas.

My PSA was high and I did a…