When is a prostate nodule a nodule and do nodules always mean prostate cancer?

Question: I have a 70 yo friend with a strong fam hx of prostate cancer — his father died of it.  Despite a psa of 1.2, he recently had a nodule felt by his family doctor and his urologist on dre, which was followed by a biopsy that was negative — no cancer, and nothing else unusual found.  His urologist told him yearly exams were all he needed at this point.  Would you be more aggressive?  Please explain.

The term “nodule” is used a bit broadly and even I in yesterdays video with Penelope spoke of a nodule in “broad strokes.”

• A true palpable prostatic cancer nodule of the prostate would most commonly show cancer on biopsy.
• It is very common for the prostate to have asymmetry and I am sure the doctor or the patient “mis-communicates” exactly what the exam revealed. I could see me telling a patient that I felt…